McCaffrey rushed 19 times for 79 yards and brought in four of five targets for 27 yards in Sunday's 20-17 loss to Seattle. McCaffrey looked healthy out there for the second consecutive game after missing the first half of the season with tendinitis in both of his Achilles tendons.

He’s not hurting, but he’s not quite himself. That was San Francisco 49ers running back Christian McCaffrey’s assessment Sunday after his performance in a 20-17 loss to the visiting Seahawks, his second game of the season after he missed the first eight contests with Achilles tendinitis.