Italy’s highest court on Thursday confirmed a slander conviction against U.S. defendant Amanda Knox for accusing an innocent man of murdering her British flatmate 17 years ago in a sensational case that polarized trial watchers on both sides of the Atlantic.

Italy’s high court has upheld the remaining conviction against American Amanda Knox, who was jailed and later acquitted of the 2007 murder of her British roommate Meredith Kercher.

The 37-year-old was fighting to clear her name after being convicted of falsely accusing a Congolese bar owner of murdering her British roommate in 2007.

Italy's highest court on Thursday upheld the conviction of American Amanda Knox for slander in a case related to the murder of her British flatmate in 2007, the final act in a legal drama lasting almost two decades.