pharmaphorum5d
Living with LHON: Achieving your dreams in the dark
But he wasn’t about to let mitochondrial disease Leber’s hereditary optic neuropathy (LHON) stand in his way, and he made his first appearance as part of Italy’s Paralympic team in 2016 ...
pharmaphorum2d
Living with LHON: Individual struggles, common challenges
Over the last few months, our Living with LHON features have looked at the individual stories of the inspirational people who have refused to let sight loss mean the end of their dreams.
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GenSight’s Optic Neuropathy gene therapy sustains efficacy over five years
LHON is a relatively rare genetic disorder of ... The trial was carried out at sites across the UK, Europe, the US and Taiwan, seeing up to 98 subjects between 2018 and 2019.
Healio28d
Lumevoq for LHON yields sustained visual acuity improvements at 5 years in phase 3 trial
The phase 3 randomized, double-masked, placebo-controlled REFLECT clinical trial enrolled 98 patients with vision loss due to Leber hereditary optic neuropathy (LHON) who received an intravitreal ...
Morningstar1mon
GenSight Biologics Announces Five-Year Efficacy and Safety Results for LUMEVOQ® Gene Therapy at the Conclusion of the REFLECT Study
The results show that five years after a one-time administration of the gene therapy, the visual acuity improvement among patients with LHON (Leber Hereditary Optic Neuropathy) was sustained while ...