In their quest to find compounds that alter disease-related proteins in new ways, researchers have developed so-called chemical inducers of proximity, or CIPs, which include molecular glues and ...

Such compounds can interfere with viral entry mechanisms, thereby reducing viral activity. "The variants of spike proteins can be divided into five distinct clusters based on the similarity of ...

Their pioneering work has been featured as a Supplementary Cover in the Journal of the American Chemical Society ... reactive sites on a target protein. The dOxa compound proved approximately ...

By combining the expansive REAL Space with the Recursion OS to predict small molecule compatibility with protein targets, the collaboration allows for the creation of smaller, highly focused libraries ...