In their quest to find compounds that alter disease-related proteins in new ways, researchers have developed so-called chemical inducers of proximity, or CIPs, which include molecular glues and ...

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Such compounds can interfere with viral entry mechanisms, thereby reducing viral activity. "The variants of spike proteins can be divided into five distinct clusters based on the similarity of ...

To be effective as a drug, an organic compound must typically fit into a cleft or pocket of a protein and alter its ... researchers to do a broad sweep of chemical space that was once impossible ...