The spleen contains many blood vessels since one of its primary functions is filtering blood. Injury to the spleen can damage these blood vessels and cause significant bleeding that leaks into the ...

CALR mutations occur in about 20% of patients with primary and post-essential thrombocythemia myelofibrosis, as per the study ...

Here, the authors target the spleen to reduce acute heart injury and improve long-term cardiac function via transient IRF7 inhibition. Neudesin is identified as an inhibitor of erythrophagocytosis ...