From The Lonely Island's Digital Shorts to Lisa from Temecula, IndieWire picks the 50 best 'Saturday Night Live' sketches of the 21st Century.

Perhaps the sketches with memorable characters like Kristen Wiig's Target Lady or Mary Katherine Gallagher from 'St. Monica's ...

During its impressive run, the show has introduced the world to some of the most iconic comedic talent of all time, including ...