The expression of many eukaryotic genes is regulated at the level of translation initiation. The first step in the initiation process is binding of the small ribosomal subunit (40S) to the mRNA.
RNAP (left, red) can directly deliver the mRNA to the entry channel of the small ribosomal subunit (left, yellow). Alternatively, and likely dominant in bacteria, RNAP (green) can interact with ...
Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...
The exosome also participates in processing small nucleolar and small nuclear RNAs (snoRNAs, snRNAs) and ribosomal RNAs (rRNAs ... from enhancers. The eukaryotic nuclear RNA exosome includes an ...
Ribosomes are composed of two subunits, the small and ... sites for ribosomal proteins, which help stabilize the overall structure of the ribosome. One of the most remarkable features of rRNA is its ...