Thanks to that hilarious opening monologue from Conan O'Brien at the 2025 Oscars, we got the perfect new meme: John Lithgow looking disappointed. As O'Brien told the audience of Hollywood's best ...

NME posted a video leveraging the meme’s popularity as a hook, tilting it, “Cillian Murphy & Timothy Spall react to ‘disappointed Cillian Murphy meme’. “You’ve got to talk about ...