Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short. Among other things, they regulate inflammatory reactions and influence ...

An international team of researchers co-led by Job Dekker, Ph.D., at UMass Chan Medical School, have identified rules that ...

This important study shows, for the first time, the structure and snapshots of the dynamics of the full-length soluble Angiotensin-I converting enzyme dimer. The combination of structural and ...

Center of Cooperative Research in Biosciences (CIC bioGUNE) Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, Spain ...

However, the existing computational methods are insufficient and inefficient to exploit enzyme structure. In this work, we introduce SEFP, a novel method leveraging enzyme point clouds for enzyme ...