Tehran said American bases in the Middle East could face reprisals if the U.S. helped repel Iranian attacks on Israel.

Israel launched “preemptive” strikes early Friday across Iran, amid growing regional tensions and concerns about Iran’s nuclear capabilities.

Shapiro served as Deputy Assistant Secretary of Defense for the Middle East until January—charged with, among other things, considering scenarios in which tensions between Israel and Iran escalated into all-out war and preparing U.

Senate Minority Leader Chuck Schumer is the only one of the top four congressional leaders not to react so far

Israel’s ongoing attacks on Iranian nuclear sites, generals, and scientists killed 78 people and wounded more than 320 on Friday, Iran’s ambassador told the U.N. Security Council, but he said “the overwhelming majority” of victims were civilians. Israel described the new wave of hostilities as the beginning of “Operation Rising Lion.”

In response to Israel’s attack, Iran fired back with more than 100 drones. NBC News’ Chief International Correspondent Keir Simmons reports more. Former NATO Supreme Allied Commander retired Gen. Wesley Clark and Senior Fellow at the Carnegie Endowment for International Peace Aaron David Miller join Ana Cabrera to examine the possibility of further attacks.

Johnson affirmed the U.S. and Israel's shared goal of preventing Iran from acquiring nuclear weapons. Israeli Prime Minister Benjamin Netanyahu stated the operation aims to counter Iran's threat to Israel's existence.

The two sides were due to meet for a sixth round of negotiations on Sunday. Tehran suggested that it had not yet decided whether to participate, given Israel’s attack on its nuclear infrastructure.