The Nose Knows: How Smell Loss Connects to Early Parkinson’s Disease Symptoms “Smell dysfunction starts very ... appear to form in the olfactory bulb (the brain region responsible for smell ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Joy Milne knew something was wrong with her husband long before doctors did. It started with a change in his scent—a musky, waxy odor she couldn’t place. Seventeen years later, when Les was diagnosed ...

In fact, olfactory dysfunction is seen in various central nervous system disorders that involve immune-mediated mechanisms, such as Parkinson’s disease, schizophrenia, Alzheimer’s disease and ...

Scientists have developed a smell test that could potentially identify those in the early stages of this neurodegenerative ...

Genes associated with lysosomal dysfunction increase the risk of Parkinson’s disease (PD), according to a study led by scientists at Northwestern University. The discovery also explains why some ...

This finding points to a possible connection between gait disturbances and autonomic dysfunction in Parkinson's disease." The doctors say that the connection between cardiovascular disease and ...

Researchers from Mass General Brigham have developed olfactory tests—in which ... diseases such as Alzheimer's disease, Parkinson's disease, chronic traumatic encephalopathy, and traumatic ...

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also ...

Researchers developed olfactory tests -- in which participants ... for neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, chronic traumatic encephalopathy, and traumatic ...