A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Parkinson’s disease affects much more than movement, with non-motor symptoms like sleep issues, cognitive decline, and autonomic dysfunction often appearing years before physical signs., Health News - ...

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that ...

A new study highlights that olfactory testing could offer a simple, cost-effective way to detect early cognitive impairment ...

Albers and colleagues are interested in whether olfactory dysfunction — the sometimes-subtle loss of sense of smell — can ...

Early symptoms for Alzheimer’s disease typically appear after age 60, and the risk increases with age. The researchers’ olfactory tests ... s disease, Parkinson’s disease, chronic ...

The Nose Knows: How Smell Loss Connects to Early Parkinson’s Disease Symptoms “Smell dysfunction starts very ... appear to form in the olfactory bulb (the brain region responsible for smell ...

In fact, olfactory dysfunction is seen in various central nervous system disorders that involve immune-mediated mechanisms, such as Parkinson’s disease, schizophrenia, Alzheimer’s disease and ...

The olfactory system ... s disease, smell dysfunction appears across various neurodegenerative conditions, albeit with different patterns. In Parkinson’s disease, smell loss is often more ...