Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question.

Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists* at Novo Nordisk in the C-terminal a-amination of peptides and ...

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid ...

Proteins serve as the fundamental components of life, composed of folded peptide chains made up of a sequence of amino acids.

Mathews Ave Urbana, IL 61801, USA The peptide precursor of McC is adenylated ... an altered terminal amino acid retain the Trojan-horse mechanism of action but target aminoacyl-tRNA synthetases ...

They may also be signalling molecules that act through interaction with specific receptors, as in peptide hormones and cytokines. Cagrilintide is a long-acting agonist of amylin and calcitonin ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Department of Chemistry, Laboratory of Peptide and Amyloid Research, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India ...

This publication is Open Access under the license indicated. Learn More ...