The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

All analyses were performed using R (version 4.4.2). Key analysis packages included Seurat (v5.1.0) for single-cell analysis and clusterProfiler (v4.12.6) for pathway enrichment analysis. A complete ...

We employed Seurat version 3.1.4 for unbiased cell clustering analysis ... variability in FOLR1 expression may contribute to the development of adaptive drug resistance (9). Our single-cell analysis ...

Research on gastrointestinal diseases, especially cancer, has mainly focused on epithelial cells, which line the surfaces of ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

In episode one of this podcast, you’ll hear a group of experts discussing base editing and how the technology is helping scientists engineer powerful cell therapies for various diseases including ...

David A. Drew, PhD, of the Clinical & Translational Epidemiology Unit and Division of Gastroenterology at Massachusetts General Hospital, is the corresponding author of a paper published in Cellular ...

Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the ...

Semarion's SemaCyte® technology transforms adherent cell assays, enabling faster, automated workflows that enhance ...

Like bacteria, archaea are single-celled organisms. Genetically, however, there are significant differences between the two domains, especially regarding their cell envelopes and metabolic processes.