NFL Week 5 odds, picks, predictions, TV and streaming information for the Sunday football game between the Arizona Cardinals ...

Brock Purdy made San Francisco 49ers and NFL history in the team's win over the New England Patriots on Sunday at Levi's ...

The San Francisco 49ers appear to be back. The team entered Week 4 with a 1-2 record and desperately needed a win over the ...

Another Sunday, another full slate of NFL action nearly in the books. And boy was the latest round of regular-season action ...

Here's where the San Francisco 49ers and the rest of the NFL stand heading into the "Monday Night Football" doubleheader.

SportsLine's model simulated New England Patriots vs. San Francisco 49ers 10,000 times and made its Week 4 NFL picks, ...

The San Francisco 49ers could struggle to get back in the win column Sunday after their meltdown against the Los Angeles Rams ...

The New England Patriots (1-2) travel to Santa Clara, California, to take on the San Francisco 49ers (1-2) in Week 4 of the ...

Our computer prediction projects a comfortable win (25-15) for the San Francisco 49ers (1-2) over the New England Patriots (1 ...

The NFL issued a $100K fine to the Rams after an inactive player shoved 49ers wide receiver Brandon Aiyuk at the end of LA's ...

The Rams were hit with a hefty fine for a scuffle that happened at the end of their win over the 49ers last week ...

It’s a late-afternoon West Coast matchup for the New England Patriots as they take on the San Francisco 49ers. Sunday’s game ...