Scientists say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as 'guardians' of mitochondria, small organelles, or subunits, within a ...

Family-linked cases can result from genetic mutations in a group of genes, including LRRK2, PARK2, PARK7, PINK1 and SNCA, although the interactions between the mutations and an individual's risk of ...

Of late, my family members tell me that I talk during sleep and seem to be enacting my dreams by kicking, punching and rotating on my bed,” he told me. On further investigations, I found that there ...

What is Parkinsonism? Parkinsonism is a neurological disorder that affects the movement of the body. It is named after James ...

Two of the proteins, Parkin and PINK1, hang around the mitochondria's membrane and work as a pair to enable the mitochondria to fuse or degrade. Abnormalities in the genes for Parkin and PINK1 are ...

Parkinson's disease is often seen as a condition that primarily affects older adults. In reality, it can impact people at any age, with 10-20% of cases appearing before the age of 50, and about half ...

Two of the proteins, Parkin and PINK1, hang around the mitochondria's membrane and work as a pair to enable the mitochondria to fuse or degrade. Abnormalities in the genes for Parkin and PINK1 are ...

Two of the proteins, Parkin and PINK1, hang around the mitochondria’s membrane and work as a pair to enable the mitochondria to fuse or degrade. Abnormalities in the genes for Parkin and PINK1 are ...

Two of the proteins, Parkin and PINK1, hang around the mitochondria's membrane and work as a pair to enable the mitochondria to fuse or degrade. Abnormalities in the genes for Parkin and PINK1 are ...

Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a new function of the DNA repair protein ATR in regulating mitochondrial homeostasis. This discovery ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. WFS1 and CISD2 regulate IP3R activity through ...