An investigational therapeutic vaccine showed clinical effectiveness in patients with human papillomavirus (HPV)16-positive ...

rates of cervical intraepithelial neoplasia (CIN) grades 2-3 and adenocarcinoma in situ (AIS), defined as CIN2+, decreased by 79%, and rates of CIN grade 3 and AIS, defined as CIN3+, decreased by ...

Human papillomavirus (HPV) vaccines are in wide use around the world owing to the widespread implementation of immunization programs for young girls before they become sexually active. The phase ...

Notable reductions in cervical ... neoplasia grade 2 (CIN2) or more severe lesions with a higher grade (CIN2 +). ...testing with HPV and LBC was no more sensitive for the detection of CIN3 than ...

Another term for cervical dysplasia is cervical intraepithelial neoplasia, or CIN. The exact cause of cervical dysplasia is not known, however it has been linked to the human papillomavirus (HPV).

Cervical intraepithelial neoplasia (CIN ... Of all 204 patients with positive endocervical margins, 18 (8.8%) had CIN2 and 186 (91.2%) had CIN3. No significant difference was observed in overall, ...

[36] Detection of E6/E7 mRNA was strongly correlated with severity of the lesion; more than 90% of CIN 3 cases and all five ... development of high-grade cervical neoplasia. HPV DNA testing ...

A study of 1.3 million women in England has provided evidence to support the extension of cervical ... grade cervical intraepithelial neoplasia, which are abnormal changes of the cells that line the ...