Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short.

Every year, thousands of tons of brown algae are extracted from the seabed to obtain compounds such as alginates, a polymer ...

Scientists have for the first time looked deep into the protein structure that may determine our vision—and discovered that ...

WE have previously demonstrated that plasma clots and whole blood clots are very resistant to the action of trypsin and α-chymotrypsin in saline but can be lysed by solutions of trypsin and α ...

This important study shows, for the first time, the structure and snapshots of the dynamics of the full-length soluble Angiotensin-I converting enzyme dimer. The combination of structural and ...

A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) reveals that enzymes are deformable machines whose mechanical specifications significantly ...

However, the existing computational methods are insufficient and inefficient to exploit enzyme structure. In this work, we introduce SEFP, a novel method leveraging enzyme point clouds for enzyme ...

To achieve their vision, they recruited experts in drug discovery with extensive biopharmaceutical experience to build a multidisciplinary integrated facility under one management structure that ...

Materials Research Laboratory, University of California, Santa Barbara, California 93106-9010, United States Department of Chemical Engineering, University of California, Santa Barbara, California ...

Now, the author has become one of the most experienced and internationally acknowledged, innovative and influential protein-structure researchers and trendsetters, one of the leaders in experimental ...

Inhibiting key enzymes vital in replication could manage the dengue virus infection. This study investigated the potential of margolonone and isomargolonone from Azadirachta indica to inhibit dengue ...