A team at UC San Francisco and Gladstone Institutes has developed new drug candidates that show great promise against the ...

Among patients with oncogene-driven advanced NSCLC who were treated with TKIs, ctDNA clearance was associated with improved survival end points.

A study uncovers intricate details about protein function at the molecular level. The discovery could transform disease diagnostics and treatment.

Phenotypic screening has re-emerged as a powerful strategy for identifying drugs based on their observable effects. Discover ...

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by researchers at UTHealth Houston, potentially paving the way for innovative ...

Proteins play a central role in virtually every disease. They are the building blocks of life, serving as essential ...

The focus of the study in dialysis patients, in whom bacterial infections often compromise tunnelled cuffed catheters - a ...

For some creatures, a lost body part is not necessarily a permanent affair. Salamanders can regrow limbs and zebrafish can ...

GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Another reason for choosing a particular modality is that it is a team’s specialty. Strategic choices can be less about determining which modality best fits a potential target than about choosing a ...