In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.

Background: Lung disease is the most overrepresented cause of death in rheumatoid arthritis (RA). Animal studies have demonstrated potentiated autoimmunity, arthritis ...

To our surprise, though, this synthetic hunger state also led to a marked drop in specific immune cells in the blood, called monocytes. These cells are part of the immune system’s first line of ...

These tissue-specific effects were secondary to reduced neutrophil infiltration, modulation of fibroblast activation and phenotype (in the heart) and attenuation of monocyte and macrophage numbers (in ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...

There’s also CT-1119, a mesothelin-targeted CAR-monocyte Carisma had been teeing up for a phase 1 trial in China in combination with BeiGene and Novartis’ tislelizumab in patients with ...

Circulating monocytes largely contribute to macrophage buildup in atheromata, which is crucial for clearing subendothelial LDLs (low-density lipoproteins) and dead cells; however, the transitional ...

PHILADELPHIA, March 31, 2025 /PRNewswire/ -- Carisma Therapeutics Inc. (Nasdaq: CARM) ("Carisma" or the "Company") today announced that its Board of Directors has approved a revised operating plan ...

This can now be tested in larger clinical trials based on these study results. The researchers analyzed monocytes – a type of white blood cells that can differentiate into macrophages in humans – in ...

The study 'Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages' led by Professor Dr Jan Rybniker, who heads the Division of Infectious Diseases at ...