Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

Decoy Therapeutics, Inc. (Decoy), a privately held preclinical biopharmaceutical company engineering the next generation of peptide conjugate therapeutics, announces that Massachusetts Institute of ...

In small nucleic acid drug development, Tsingke drives innovation in synthesis, modification, delivery, and scale-up. With an end-to-end service model-from sequence design to validation-the company ...

Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Campus JK, Rodovia MGT 367 - Km 583, n° 5.000, Alto da Jacuba, CEP 39100-000 Diamantina, MG, Brazil ...

Department of Plant Pathology and Nematology, University of São Paulo (USP)/Luiz de Queiroz College of Agriculture (ESALQ), Av. Pádua Dias, 11, Piracicaba, São Paulo 13418-900, Brazil Department of ...

We developed a novel set of peptide nucleic acid (PNA)-based FISH probes with optimal target specificity by analyzing the variations in 16S ribosomal RNA sequence across all bacterial species." ...

More information: Sungho Kim et al, Fast and accurate multi-bacterial identification using cleavable and FRET-based peptide nucleic acid probes, Biosensors and Bioelectronics (2024). DOI ...

Codexis has also successfully completed development of the first generation of its core ECO Synthesis™ enzymes, having met the pre-specified criteria to support scaling to industrial capacity.

This shows that antisense transcripts do not simply generate non-coding regulatory RNAs but are also translated to provide a source of peptide substrates for the MHC-I pathway. Uncovering the origin ...