IDRX-42 is a selective small molecule inhibitor targeting mutations in the KIT tyrosine kinase, which are implicated in the pathogenesis of GIST ... is also an ongoing phase 2 study in non-infectious ...

The pathogenesis of AS is poorly understood ... pain plus at least two other typical features of spondyloarthropathy (for example, enthesitis and uveitis) is highly predictive of early AS.

A cohort study finds children with early-onset atopic dermatitis to be at increased risk for uveitis, highlighting a need for ophthalmologic monitoring in youth.

What Are Treatments for Uveitis? Uveitis is the inflammation of your uvea — the middle layer of your eye. It can happen for many reasons, but up to 70% of cases have unknown causes. It can ...

Pathogenesis is the term that is used to describe the origin and development of a disease. Distinct proteolytic pathways share convergent activation patterns in many pathological contexts. Two new ...

Compr Ophthalmol Update. 2007;8(1):39-49. Disclosure: Dr. Balcer has served as a consultant for development of visual outcomes for trials for Biogen Idec, Merck Serono, Sirtris Pharmaceuticals ...

A study found that children with early-onset atopic dermatitis have a higher risk of developing uveitis and should be closely monitored for its onset. Taiwanese investigators found in their cohort ...

Increasing evidence indicates that microbial agents promote non-infectious uveitis, but the natural history of immune responses to pathogens in patients remains unexplored. We determined intraocular ...

ucl.ac.uk BACKGROUND/AIMS Idiopathic recurrent acute anterior uveitis (RAAU) is a common reason for attendance at ophthalmic casualty departments. Patients who suffer with this condition may have ...

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