Big Ten football kicks off this weekend as No. 3 Ohio State returns home against Purdue. Let’s take a look at the latest predictions for the matchup from an exp

Preview the Ohio State Buckeyes vs. Purdue Boilermakers college football matchup, with score predictions, stats, and game information.

Ohio State is a 38.5-point home favorite against Purdue this week, according to DraftKings. The line provides a mixture of belief in the Buckeyes and worry about the Boilermakers. Ohio State is beating unranked opponents by an average of 33.3 points per game. Meanwhile, Purdue is losing to ranked foes by nearly 32 points per game.