CCN2025: Annual Conference on Cognitive Computational Neuroscience- 8th 12 &#x2013 15 August 2025Amsterdam, The Netherlands View conference website International Society for Neurochemistry (ISN) ...

Anatomy explorers have charted a new path myeloid cells use to access the brain. On 3 June in Neuron, scientists led by Lindsay Hohsfield and Kim Green, both at the University of California, Irvine, ...

To narrow down the number of scents needed for such a test, Li first ranked each of the 16 SST-ID and 40 UPSIT scents for their ability to distinguish PD/DLB from controls in three cohorts—the De Novo ...

Besides cushioning the brain, CSF washes away waste such as neurotransmitters, metabolites, and proteins, including proteins that aggregate—such as Aβ and tau. After circulating through the brain, CSF ...

For years, scientists have been working toward blood tests for Alzheimer’s disease that could be used routinely in clinical practice. Now, they are on the cusp. At this year’s ADPD conference, held ...

Their analysis of three large population studies found that age-adjusted prevalence has dropped by a whopping two-thirds over the last 40 years. In other words, every successive birth cohort has a ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...

Old drugs die hard. Despite a string of negative Phase 3 trials, HMTM, a derivative of the malaria drug methylene blue, resurfaced again at AD/PD 2024, held March 5-9 in Lisbon, Portugal. TauRx CEO ...

Not so long ago, a blood test for Alzheimer’s disease seemed a pipe dream. Now, after years of study, the field is awash with sensitive assays that signal the proteopathic culprits Aβ and tau ...

The latest effort to rewrite the diagnostic criteria for Alzheimer’s disease has stirred more than a little controversy. While the proposed revisions have garnered praise from researchers for more ...

All Signs Point to Plaque Clearance Tangle accumulation has slowed in all successful anti-amyloid antibody trials so far—except in the Trailblazer-Alz2 study of donanemab. That trial posted the ...

Meet the New Kid—Trontinemab Struts Its Stuff Roche’s brain shuttle is a Fab antibody fragment that binds the transferrin receptor. After binding this receptor on vascular endothelial cells, the ...